Aida Ortiz García

I am a very enthusiastic and positive person. I did my bachelor in Biology in Spain and my master in Bioinformatics in Leuven, Belgium.  I have a huge interest in transcriptome analysis, but at the same time I am open to expand my knowledge and experience to other fields involving the analysis of biological data.

Master's Thesis in Glioblastoma (KU Leuven-VIB), KU Leuven, Belgium. | September 2021 - August 2022 - Investigating safer ADCs therapies for Glioblastoma. Data used: GBM and breast cancer bulk and scRNA-seq data.

Student Job at VIB Leuven, Belgium | 6th September 2022 - 30th September 2022 - Finding plasma membrane biomarkers in Alzheimer Disease (AD) and healthy brain. Data used: mouse and human scRNA-seq and snRNA-seq data

Intership at Instituto Extremeño de Reproducción Asistida (IERA) Badajoz, Extremadura| January 2020. Wet-Lab: In vitro fertilization (IVF), seminograms, oocytes vitrification.

It was when I started my master thesis in Bioinformatics this year when I developed my interest for omics analysis, specially, transcriptomics. I did my master’s thesis in KU Leuven-VIB (Center for Brain Disease Research), Department of Neurodegenerative Diseases. Specifically, I worked with Glioblastoma (GBM). The aim of the thesis was finding a more targeted therapy for patients with GBM in order to decrease the side-effects of the treatment. For that, we focused on bispecific antibody-drug conjugates (ADCs), and tried to find pair of genes that co-express in high level in tumor tissue/cancer cells and at least one of them in low level in healthy tissue/non-cancer cells. During the thesis I performed bulk RNA-seq and single-cell analysis, as well as pseudobulk analysis. I used both in-house and publicly available data.

Right after finishing my master's thesis I did a student job for one month where I was involved in a project with my two supervisors of my master's thesis. My job was to find plasma membrane markers in Alzheimer's and control brains. For that, I used in-house and publicly available human and mouse brain scRNA-seq and snRNA-seq datasets.