- You will plan & execute lab activities (Analytical Ultracentrifugation – AUC, Dynamic Light Scattering – DLS, and Size-Exclusion Chromatography –SEC) in the GMP (Wavre) and non-GMP (Rixensart) environment.
- You will provide support and technical advice to lab technicians and participate in the planning of their activities.
- You will participate in lab organization and maintenance, e.g., ordering reagents and follow-up of instruments maintenance/repair in collaboration with technicians & lab supports.
- You will participate in method development according to Quality by Design (QbD) guidelines, in a phase-appropriate manner, and provide fit-for-purpose analytical methods in interaction with Analytical Product Leaders & Subteams (APL & AST), as well as Industrialization Leaders (AIL).
- You will interpret and report results after an extensive check of the raw data quality and participate in the double-check of results.
- You will be involved in generating appropriate analytical documentation, including procedures, protocols, and reports (development, technical, qualification, validation).
- You will present results in internal meetings (within the team, to ASTs, etc.).
- You will interact with other Technical R&D (TRD) departments (Drug Substance, Drug Product, Statisticians team), as well as the Preclinical department or GIO/QC organizations.
- You will participate in scientific/technology watch in your domain of competency.
- Master's degree in Chemistry, Biochemistry, Biophysics, Biology, Bioengineering, Chemical Engineering, Pharmacy, or other relevant discipline.
- Extensive experience in DLS and AUC.
- Strong experience in working in a GMP environment.
- Experience in size-exclusion chromatography (HPSEC) is a plus.
- Awareness of Quality by Design principles.
- Knowledge of method qualification/validation principles.
- Sound scientific methodology and thinking, autonomy, and commitment to solving problems and bringing innovative solutions to the team.
- Communication skills (oral & writing), ability to engage the team; open-minded, result- and quality-oriented.
- Microscopy-related techniques (Transmission Electron Microscopy (TEM, cryo-EM), Scanning Electron Microscopy (SEM), confocal),
- Nanoparticle Tracking Analysis (NTA),
- Static Light Scattering (SLS),
- Field-Flow Fractionation (FFF), and
- Multi-Angle Light Scattering (MALS).
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Associate Scientist in Sizing - Rixensart, België - 1849 GlaxoSmithKline Biologicals S.A.
Beschrijving
As an Associate Scientist of the Sizing & Morphology platform in Analytical R&D (ARD), you will plan & execute lab activities in a team in charge of size-based separations & light scattering techniques. Also, you will participate in the analytical method development according to Quality by Design principles, from early vaccine candidates up to validation for phase III programs.
Your responsibilities:
Basic Qualifications:
Preferred qualifications:
If in addition to AUC, DLS and SEC if you have the competencies/experience in the following domain, it would be a plus:
#GSKVaccines #LI-GSK
If you have a disability and require assistance during the course of the selection process, you will have the opportunity to let us know what specific assistance you require in order to make suitable arrangements.
Why GSK?
Uniting science, technology and talent to get ahead of disease together.
GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).
Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.
Important notice to Employment businesses/ Agencies
GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK.
