Microbial Strain Development Scientist - Fleurus, België - HANDARY

HANDARY

Geverifieerd bedrijf

Fleurus, België

1 week geleden

Geplaatst door:

Sophie Dubois

beBee Recruiter

Beschrijving

Handary leads the natural food shelf-life industry, sole expertise in preventing microbial spoilage, discoloration, off-flavor and nutrient loss during food storage.

We designed and produced 26 well-known brands of natural shelf-life ingredients distributed worldwide. Currently, we look for 1 Microbial Strain Development Scientist in improving production yields of food antimicrobial strains in Belgium.

Tasks & Responsabilities:

Improve the production yields of industrial strains including Natamycin, Polylysine, Nisin and Lysozyme;
Benchscale high cell density microbial fermentations toward optimization of bioprocess parameters such as media formulation and expression development;
Benchmarking studies focused on understanding strain performance and meeting project goals centered around titer, production rate, and yield metrics;
Construct and validate highthroughput, platebased fermentation workflows for screening / characterization purposes and bioprocess development;
Develop technologies and/or methods oriented around strain adaptation/evolution
Collaborate internally with the Strain Engineering, Analytics, and Process Development & Scaleup Groups as well as externally with Handary's partners to guide strain development, fermentation work plans, and scaleup efforts
Establish a data management system to track fermentationbased data as well as implement statistical and computational analyses on large data sets
Lead the expansion and maintenance of the company's fermentation capabilities: procurement of equipment, buildout, equipment troubleshooting & repair
Work with CMOs to facilitate the successful scaleup of inhouse fermentation processes from the bench to commercial levels.

Requirements:

PhD or MS in Chemical Engineering, Biochemical Engineering, Fermentation Science, or a related discipline
PhD with 2+ years (or MS degree with 6+ years) of industrial/startup experience working directly with labscale and/or pilotscale fermentations is required
Deep aptitude for & handson expertise with various aspects of fermentation R&D such as media design, fedbatch & chemostats operations, microaerobic & anaerobic fermentations, strain evolution studies, scaledown fermentation technologies (BioLector, Ambr), and highthroughput/automated culture development
Experience with implementing design of experiment (DoE) methods for strain screening/characterization and bioprocess development
Demonstrated success working both individually and crossdisciplinary to balance multiple independent experiments/projects
Solid fundamental knowledge of biochemical engineering principles including mass balance, mass transfer, reactor design, growth dynamics, and correlations between microbial physiology and fermentation/bioprocess performance
Familiarity with various bioreactor systems and control software; fermentationrelated accessory technologies; and statistics, data analysis tools, and data management software
Excellent time management, experience managing engineers/technicians, and a keen sense for efficiently driving multiple projects in parallel
Ability and willingness to work extended days and weekends

Application Process

EOE STATEMENT

We are an equal employment opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, age, national origin, disability, military status, genetic information, sexual orientation, or other applicable protected classes.